Zero Candida

The Problem

Candidiasis is a fungal infection that causes irritation, discharge
and intense itchiness of the vagina and the vulva – the tissues at
the vaginal opening. Until recently this disease was poorly
understood. The most recent studies associate some cases of
candidiasis with a weakened immune system. There is strong
scientific support that Candidiasis is not an STD (Sexually
Transmitted Disease).

candida fungus
candida-position

Current
Treatment

Standard therapy

  • Vaginal ovules
  • Creams
  • Oral drugs

Alteration in the immune system

  • Immunosuppressive therapy
    (organ transplant, cancer, AIDS)
  •  Chronic candidiasis

Low drug bioavailability

  • Side effects of antifungal drugs
  • Short time of drug efficiency
  • High re-currence

Reduction in the intracellular
level of drug

  • Biofilm presence
  • Modern world overuse and
    low response to drugs

The Market

Candidiasis affects 3 out of 4 women at some point in their lifetime.
Candidiasis recurrence affects hundreds of millions women per year worldwide.
The highest prevalence (9%) is seen in women between 24 and 34 years old.

The burden cost spend for Candidiasis treatment annually worldwide
(in developed countries):

tjhe-market-fungus

Our Solution

The novel way to treat Candidiasis

We have developed a tampon-like device which is a combination of a
light source with a selected wave-length and intensity, and a transparent
gel based drug delivery system as well as maintaining the optimum Ph in
the vagina. The device is used only at night for 3 consecutive nights,
providing an optimal solution for the treatment of Candidiasis.

Standard Model

Scientific and Clinical Board

Dr. Irene Zeitoun, PhD, MBA

Dr. Irene Zeitoun, PhD, MBA
COO & Chief Research Officer

Dr. Zeitoun has over 20-year experience in managerial roles in biotech and pharma ventures.
Irene was the WW Marketing
Director of Mindset
BioPharmaceuticals and
MindGenix in the field of
Alzheimer’s Disease. She was the
Director of R&D at Ester
Neurosciences and the Project
Manager of the Israeli National
Tissue Bank for research
Purposes. Dr. Zeitoun was the
Manager of Industrial Research
Services of Ramot at Tel-Aviv
University. She was the BD &
Marketing Manager of the
accelerator Targetech and was
the Operations Manager of
Targia Pharmaceuticals.

Prof. Asnat Walfisch
Clinical Board Chairman

Prof. Walfisch has earned her
MD at the Ben Gurion
University (Valedictorian). She
later completed her residency
in OBGYN at “Soroka” and
“Sheba” Tel Hashomer Medical
Center, and her fellowship in
Feto-maternal Medicine at
Toronto University. Prof.
Walfisch is the author of some
150 scientific publications in
Gynecology and Feto Maternal
medicine. She was the Head of
the Obstetrics and Gynecology
Department at Hadassah Mt.
Scopus, and is currently the
head of the Helen Schneider
Woman’s Hospital at Rabin
Medical Center.

Prof. Tal Biron
Clinical Board Member

Prof. Biron is the head of the
OBGYN department of Meir
Medical Center, Clalit
Healthcare.
Prof. Biron is the chairperson
of the Israeli society of
Maternal-Fetal Medicine.
She is a full clinical professor
at Tel Aviv University.
She earned her M.D. at the
Technicon and her OBGYN
residency at Meir Medical
Center.
Prof. Biron completed a
fellowship in maternal-fetal
medicine at Washington
University (MO, USA).

Susan Alpert, Ph.D., M.D.
Board Advisor

Susan Alpert, Ph.D., M.D.is
currently the principle of
SFADC LLC (aka SFA Regulatory,
LLC), a one person firm focused
on the strategies needed to
place medical devices and
other medical products into the
global market. She was a
Corporate Senior Vice
President for Global Regulatory
at Medtronic, Inc. and prior to
that VP Regulatory Science at
C.R. Bard, Inc. She previously
worked at the US FDA where
she held a variety of
management positions.
Susan is a microbiologist and
pediatrician with a specialty in
infectious diseases.

Dr. Asher Holzer
Director

A serial entrepreneur with
over 30 years of experience
as a member of senior
management, mainly in the
field of medical equipment.
Founded, issued at NASDAQ
and served as chairman of
the board of directors of
many companies, including:
UroGen, InspireMD BioSig,
TheraCoat and more. Holds
a doctorate in nuclear
physics from the Hebrew
University.

Prof. Ehud Davidson
Director

The CEO of the largest
health maintenance
organization (MHO) in the
State of Israel, Clalit (with
holds 52% of the market
share), led the treatment
of the majority of Israeli
patients in the
community, as well as in
Clalit hospitals, he also
led the huge projects of
Covid-19 vaccination in
Israel, which were very
successful.

Board Members

Eli Ben Haroosh
Founder, Director

Served up until recently as
President of the stockexchange
company Vonetize
for several months until
2020. In the last 6.5 years
served and Vice President
and CEO of Premier – Dead
Sea and was responsible for
sales in 74 countries and in
close to 1000 sales points
totaling tens of millions of
dollars a year. Moreover,
Ben Haroosh serves as the
director of several
companies and as the
president of Mariana Inc.
which works in the field of
cannabis research and
development.

Dr. Asher Holzer
Director, Founder

A serial entrepreneur with
over 30 years of experience
as a member of senior
management, mainly in the
field of medical equipment.
Founded, issued at NASDAQ
and served as chairman of
the board of directors of
many companies, including:
UroGen, InspireMD BioSig,
TheraCoat and more. Holds a
doctorate in nuclear physics
from the Hebrew University.

Prof. Ehud Davidson
Chairman of the board

The CEO of the largest
health maintenance
organization (MHO) in the
State of Israel, Clalit (with
holds 52% of the market
share), led the treatment
of the majority of Israeli
patients in the community,
as well as in Clalit
hospitals, he also led the
huge projects of Covid-19
vaccination in Israel, which
were very successful.

Prof. Asnat Walfisch
Director

Prof. Walfisch has earned her
MD at the Ben Gurion
University (Valedictorian). She
later completed her residency
in OBGYN at “Soroka” and
“Sheba” Tel Hashomer Medical
Center, and her fellowship in
Feto-maternal Medicine at
Toronto University. Prof.
Walfisch is the author of some
150 scientific publications in
Gynecology and Feto Maternal
medicine. She was the Head of
the Obstetrics and Gynecology
Department at Hadassah Mt.
Scopus, and is currently the
head of the Helen Schneider
Woman’s Hospital at Rabin
Medical Center.

Prof. Tal Biron
Director

Prof. Biron is the head of the
OBGYN department of Meir
Medical Center, Clalit
Healthcare.
Prof. Biron is the chairperson
of the Israeli society of
Maternal-Fetal Medicine.
She is a full clinical professor
at Tel Aviv University.
She earned her M.D. at the
Technicon and her OBGYN
residency at Meir Medical
Center.
Prof. Biron completed a
fellowship in maternal-fetal
medicine at Washington
University (MO, USA).

Susan Alpert, Ph.D., M.D.
Director

Susan Alpert, Ph.D., M.D.is
currently the principle of SFADC
LLC (aka SFA Regulatory, LLC), a
one person firm focused on the
strategies needed to place
medical devices and other
medical products into the global
market. She was a Corporate
Senior Vice President for Global
Regulatory at Medtronic, Inc. and
prior to that VP Regulatory
Science at C.R. Bard, Inc. She
previously worked at the US FDA
where she held a variety of
management positions.
Susan is a microbiologist and
pediatrician with a specialty in
infectious diseases.

Board Members

Dr. Zeev Schmelzer
Patent Advisor

Patent attorney in the field of
mechanics, medical equipment,
biology and medicine, with over
13 years of experience in the field.

Niv Keidar
Product Manager

R&D Project manager for
medical device.
B.sc in Biomedical engineering
from BGU.
M.sc in biotechnology from Tel-
Hai collage.
Deep knowledge in
development of medical device
from prototype to production,
according to ISO-13845.
Experience in managing multilayer
project for creation of new
medical device.

Dov Oppenheim
Chieff Product Designer

More than 25 years experience in
mechanical, Industrial, and
electronic design, and production
of medical devices, including
Dario (Nasdaq: DRIO) a
revolutionary digital health
solution for blood glucose
detection. Dov has established
several production lines, for
several medical device systems,
and is very familiars and managing
global supply systems and
operation activities.

Gad Benett
Patent Advisor

Patent Attorney & Managing Partner at
Paulina Ben-Ami, Patent Attorneys
Paulina Ben-Ami is a boutique IP firm,
serving hundreds of clients both nationally
and internationally.
Before, Gad worked in business
development and product management for
innovative start-ups in Silicon Valley and
elsewhere. Before, Gad was a software
engineer.
Gad holds a Master’s degree in Software
Engineering from the University of Paris 2,
and an MBA from the McCombs School of
Business at the University of Texas at Austin.

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